Category: The Fever (Page 4 of 4)

ResurgentMalaria.com

My new website, ResurgentMalaria.com, launched this week in advance of World Malaria Day on April 25. ResurgentMalaria.com explores the politics and history of malaria, one of humankind’s most fierce scourges. This is a disease we’ve known how to prevent and cure for over 100 years, but which still infects 500 million a year and kills over 1 million. Why that is is the subject of ResurgentMalaria.com. (Clue: it’s a bigger problem than just a failure of donations for bednets or grants for vaccine research.)

Check out a podcast about ResurgentMalaria.com from the UN Millennium Campaign here. And a blog post from Prescription Access Litigation (PAL) here.

malaria website coming soon…

I’ve spent the last month putting together material for a new websiteon the topic of my next book: resurgent malaria. MalariaResurgent.comwill be a provocative, opinionated take on humankind’s oldest disease,why it still plagues us, and what can be done about it. There’ll bestories, history, videos, and most of all, conversation. The site shouldbe live soon after the New Year. Stay tuned for more…

NYT on fighting malaria with bednets

The New York Times ran a piece on distributing insecticide-treated nets for malaria today. It is an old story. There were long and tedious workshops on it at the last malaria conference I went to in Cameroon two years ago. I agree that bednets should be considered a social good, but it isn’t right to assume that every net distributed is a net used (and a life saved). It may be true that the very poorest don’t buy nets, but it is also true that many people (rich and poor) don’t use free nets, either. It isn’t just a technical problem of distribution, there are larger cultural, economic, and health issues.

When I went to Cameroon, I visited villages where ExxonMobil had said it had distributed thousands of free nets; and yet the people I met at the malaria clinic there said they didn’t know a single person who actually used one. I got the same response when I asked people at a malaria clinic in Malawi, and in Panama. They said the nets are hot, that people have different priorities (like using the netting for fishing, wedding veils, curtains), that the nets get holes in them, that malaria isn’t taken seriously enough, and so on.

It sounds nice for donors to be able to say they distributed lots and lots of free nets (marketing the nets is slower), but they should also track how many people actually use the nets.

Newsweek gets it wrong on malaria

Newsweek’s short piece on malaria in Africa (September 24, 2007) is full of misinformation and mythology. For example, there has never been any continent-wide malaria control in Africa, as the lead sentence brazenly states; mosquitoes develop resistance to DDT by exposure to brand-name pesticides sold by Western chemical companies like BASF and others, not just by African farmers illegally using DDT on their fields; the main reason DDT wasn’t used in Africa for so long is because the EU and others told African farmers they wouldn’t buy their farm products if they did; and there’s evidence to suggest that malaria problem in Zambia has not gotten better, it has been worsening, and the mining companies’ whose work the article lauds have been the subject of riots.
None of these counter-points are speculative but near-consensus opinions in the malaria field. It is strange to see the mainstream press diverge so much from expert opinion: smells to me like politics eclipsing science.
Check it out: The Doomsday Spray: To fight malaria, African nations are turning to DDT.

Will genetically modified mosquitoes end malaria?

I recently asked a bunch ofnurses at a NIH-funded malaria research clinic in Malawi where all thelocal malarial mosquitoes bred, and they answered in unison–“in theswamp.” Not so, said the mosquito biologist in the next building over.In fact the bugs that were killing their patients nursed their young inthe puddles right outside the hospital’s unscreened windows.
To think that we could develop a man-made mosquito–our ownsuper-mozzie–more adept than those in the wild, with their greatdiversity of habits and lifestyles greatly underestimates the wilinessof these dappled flies. Stalked by pathogens, relied upon by no creature,these insects have thrived for over 100 million years, in almost everyplace where the sun shines and the rain falls, however seldom. They’refantastically good at it. Some GM mosquito might beat a few of thesehardy survivors, in some places, at some times, but they couldn’t beatthem everywhere.
GM mosquitoes surely will teach us somethingabout the spread of malaria but they won’t end it. As with DDT, there’sno one-size-fits-all solution to malaria, our most ancient scourge, tryas we might to find one.

Tina Rosenberg on the diseases of the poor

Tina Rosenberg’s long opinion piece in today’s New York Times brings much needed attention to the plight of “poor people’s diseases,” from sleeping sickness to tuberculosis (“The Scandal of ‘Poor People’s Diseases,’” New York Times, March 29, 2006). But her argument about malaria—that more DDT would vanquish the disease—is all wrong.

The basic gist of the argument is thus: Americans wiped out malaria using DDT, but because über-green Rachel Carson crusaded against the insecticide in Silent Spring, we self-righteously deprived the rest of the world of the miracle toxin. Two conclusions can be drawn from this little tale. One: post-Carson environmentalists have the blood of Africans dripping from their hands. Two: To quote from the title of a previous Rosenberg story on the subject, “What the world needs now is DDT (New York Times, April 11, 2004)

There are several problems with this story. The first is that DDT didn’t wipe out malaria in the United States.

For the rest of this piece, please see http://www.thenation.com/doc/20060417/shah

Genetically modified mosquitoes?

To think that we could develop a man-made mosquito–our own super-mozzie– more adept than those in the wild, with their great diversity of habits and lifestyles greatly underestimates the wiliness of these dappled flies.
Stalked by pathogens, needed by no creature, these insects have neverthless thrived for over 100 million years, in almost every place where the sun shines and the rain falls, however seldom. They’re good at it. Some GM mosquito might beat a few out, in some places, at some times, but they couldn’t win everywhere. As with DDT, there’s no one-size-fits-all solution to malaria, try as we might to find one.

GM mosquitoes!

The news media is in a big kerfuffle over reports of a new geneticallymodified mosquito that is resistant to malaria, and all the strongerthan wild mosquitoes for it. Sounds perfect, right? Stronger bugs thatfight off the parasite would easily eclipse the local weaklings thatfall prey, and soon enough, there’d be no more malaria.
And yet…each malarial locale is as unique as a snowflake, withparasites specifically adapted to local mosquitoes, which are of acertain breed, a just-so strain, with their own uniquely finickyhabits. There are over a dozen different species of Anophelesmosquitoes that effectively transmit human malaria. Some thrive inshady running water, some in still sunny puddles, others in saltymarshes, some in forests, others in deserts. Some bite at night, othersat dusk, some feed on cows and horses, others solely on humans. We knowprecious little about this great diversity of anopheline habits, andcan barely tell the critters apart, but genetic studies tell us thatthey’re continuing to break into ever more species. Even as I write,wild malarial mosquitoes are transforming themselves to more fullyexploit their local environs, like water to a cup, in ways we can onlydimly grasp.
To think, then, that we could develop our own mosquito, one thatwould be stronger and more adept in all of these specific localhabitats–our own super-mozzie–greatly underestimates the resilienceof these dapple-winged flies. The GM mosquitoes currently developed arejust a proof-of-concept, and they’ve been tested only against mousemalaria, but even if their development progressed, they could onlyconceivably work in some places, at some times. They couldn’t workeverywhere. Just as with DDT, there’s no one-size-fits-all, try as wemight to find one.

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